By Dr Tracey Bell
Patients often ask me, “Tracey, what’s new in non-surgical aesthetics?”
And while there’s always something new — polynucleotides, exosomes, and other biostimulating trends — one treatment I still swear by for consistent, long-term results is PRX-T33.
It’s elegant, evidence-based, and delivers visible improvement in texture, tone and firmness — without needles, peeling or downtime.
The Development of PRX-T33
PRX-T33 was created by WIQO Med in Italy, a company renowned for its clinical research in biorevitalisation.
It was developed after years of studying how to harness the power of trichloroacetic acid (TCA) — traditionally used for skin peels — without the downtime or trauma that TCA often caused.
The breakthrough came when scientists discovered that by combining 33% TCA with hydrogen peroxide, they could modulate its penetration: the hydrogen peroxide stabilises the acid, allowing it to pass through the epidermis without exfoliating or burning, while still stimulating activity in the dermis, the deeper layer where collagen is made.
To this they added kojic acid, a natural brightening agent that reduces pigmentation and enhances luminosity.
So PRX-T33 is a true medical innovation — a next-generation peel without peeling, offering controlled dermal stimulation rather than surface damage.
How PRX-T33 Works
PRX-T33 works through a process known as biostimulation.
The TCA acts as a messenger, triggering fibroblast activity within the dermis. These fibroblasts are the skin’s natural repair cells responsible for producing collagen, elastin and ground-substance proteins that keep our skin firm and youthful.
The hydrogen peroxide gently opens micro-channels in the skin, enhancing absorption while preventing the irritation and crusting typical of older peels.
Meanwhile, kojic acid helps to regulate melanin production, leading to a more even skin tone.
In simple terms:
- It penetrates deeply without damaging the surface.
- It activates cellular renewal.
- It boosts collagen synthesis over time.
What Patients See and Feel
During treatment, patients often describe a mild tingling or warmth, but there’s no pain or discomfort.
After the treatment, the skin looks immediately brighter, tighter and more hydrated.
Over the following 2–3 weeks, as new collagen forms and the dermal structure strengthens, you’ll notice:
- Reduced fine lines
- Improved elasticity and firmness
- Smaller pores and refined texture
- A glowing, healthy radiance
Because it doesn’t strip the surface, there’s no redness or peeling — just a fresh, polished finish that improves over time.
The Treatment Itself
Each PRX-T33 session takes about 40 minutes and follows these precise steps:
- Consultation & Cleanse: We discuss your goals and assess your skin before cleansing to remove any oils.
- Application: The PRX-T33 solution is massaged firmly into the skin using a special technique that ensures even, deep penetration. Several layers may be applied depending on your skin type.
- Neutralisation: The product is then removed, and a soothing moisturiser and SPF are applied.
You can return to normal activities immediately — no flaking, no redness, no downtime.
Course and Maintenance
Most patients choose a course of four treatments, spaced one week apart, for optimal collagen stimulation.
After this, maintenance treatments every 2–3 months help maintain the glow and firmness.
Why I Rate PRX-T33 So Highly
PRX-T33 stands out because it doesn’t rely on trauma or injury to stimulate repair. Instead, it encourages your skin’s natural regeneration in a controlled, safe and scientifically proven way.
It can also be combined with virtually any other aesthetic treatment — from microneedling and radiofrequency to fillers, anti-wrinkle injections, or laser rejuvenation.
It amplifies results by improving overall skin quality, hydration and elasticity.
I’ve found it particularly effective for:
- Fine lines and mild laxity
- Dull or sallow complexions
- Acne scarring and stretch marks
- Pigmentation and uneven tone
- Tired, ageing skin
Key Benefits of PRX-T33
Stimulates collagen and elastin naturally Tightens and firms without peeling
Evens pigmentation and brightens complexion
Hydrates and plumps the skin
Minimal discomfort, no downtime
Suitable for all skin types and all seasons
The Results
What patients love most is the instant freshness — that healthy, glass-like glow you see within minutes.
Over time, the results become more structural: firmer skin, improved texture and a lifted appearance.
After a course of treatments, the skin looks not only better but truly revitalised from within.
My Professional View
After more than three decades in aesthetic medicine, I’ve tried almost every collagen-stimulating technique available — and PRX-T33 remains one of the most scientifically sound, results-driven and versatile treatments I’ve seen.
It offers all the benefits of a peel and a booster, without any of the drawbacks.
Whether used alone or as part of a tailored skin-rejuvenation programme, PRX-T33 consistently delivers that youthful, healthy, confident glow we all want.
If you’d like to learn more or see if PRX-T33 is right for you, visit us at Tracey Bell Clinics or explore:
https://traceybell.co.uk/non-