A calcifying epithelial odontogenic tumour (CEOT), also known as a Pindborg tumour, is a rare and benign odontogenic (related to tooth development) tumour that arises from the dental tissues. It is named after Danish pathologist Jens J. Pindborg, who described it in 1955. CEOT typically occurs in the jawbones, most commonly in the mandible (lower jaw) and the maxilla (upper jaw).
Signs and Symptoms
The clinical presentation of a calcifying epithelial odontogenic tumour can vary, but common signs and symptoms include:
- Slow-growing swelling or lump in the jaw area.
- Pain or tenderness in the affected region.
- Displacement of adjacent teeth or resorption of tooth roots.
- Changes in occlusion (bite) due to the tumour’s growth.
- Paresthesia (numbness or tingling) of the lips, chin, or tongue if the tumour compresses nearby nerves.
Incidence: CEOT is relatively rare, accounting for approximately 1-3% of all odontogenic tumours. It can occur at any age but most frequently affects individuals between 20 and 50. There is a slight preference for males compared to females, but it can happen in both sexes.
Causes: The exact cause of calcifying epithelial odontogenic tumours remains unclear. However, like other odontogenic tumours, it is believed to arise from the remnants of odontogenic epithelium (tissues that give rise to teeth) or the lining of odontogenic cysts. Genetic and environmental factors may contribute to the development of CEOT, but further research is needed to understand its aetiology fully.
Treatment: Treatment of CEOT usually involves surgical removal of the tumour. The approach may vary depending on the size and location of the tumour and whether it is causing any complications. In most cases, if the tumour is completely excised, the prognosis is excellent, and recurrence is uncommon.
For more information, please read this case report from the National Journal of Maxillofacial Surgery: Calcifying-epithelial-odontogenic-tumor-Pindborg-tumor.pdf